Ixazomib Impurity 75 CAS CATO-C4X-126775
| CAS No. | CATO-C4X-126775 |
| Molecular Formula | C22H30BCl2NO3 |
| Molecular Weight | 438.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Ixazomib Impurity 75 (CAS CATO-C4X-126775) is a certified pharmaceutical impurity reference standard with the molecular formula C22H30BCl2NO3 and a molecular weight of 438.20 g/mol.
Based on its molecular formula C22H30BCl2NO3, Ixazomib Impurity 75 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 438.20 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H30BCl2NO3 |
| Molecular Weight | 438.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ixazomib Standards
- Ixazomib Impurity 71 (CAS 2920604-29-9)
- Ixazomib Impurity 20 (CAS CATO-C4X-126720)
- Ixazomib Impurity 35 (CAS CATO-C4X-126735)
- Ixazomib Impurity 86 (CAS CATO-C4X-126786)
- Ixazomib Impurity 87 (CAS CATO-C4X-126787)
- Ixazomib Impurity 46 (CAS CATO-C4X-126746)
- Ixazomib Impurity 47 (CAS CATO-C4X-126747)
- Ixazomib Impurity 48 (CAS CATO-C4X-126748)
Recommended Standards
- (E)-6-(2-((4-iodophenyl)amino)vinyl)pyrazolo[1,5-a]pyrido[3,4-e]pyrimidine-3-carbonitrile (CAS 338966-86-2)
- 1,3-Bis(2-(5-bromothiophen-2-yl)ethyl)urea (CAS 2432029-02-0)
- Ethyl 2-{2,4-dichloro-5-[5-(4-nitrophenyl)-1H-1,2,3,4-tetrazol-1-yl]phenoxy}acetate (CAS 338961-66-3)
- 6-bromo-2-[(E)-2-[4-(trifluoromethoxy)phenyl]ethenyl]quinoline-4-carboxylic acid (CAS 926199-81-7)
- Avanafil Impurity 46 (CAS 1624833-89-1)
- Loratadine Impurity 41 (CAS CATO-C4X-142641)
- Alfuzosin EP Impurity E HCl (CAS 1796934-51-4)
- 5-((4-(3-Methylbutanamido)phenyl)amino)-5-oxopentanoic acid (CAS 940214-39-1)
- Betamethasone 21-Acetate-d3 (CAS CATO-CCAD303552)
- Enzalutamide Impurity 62 (CAS 1895865-08-3)
- 2-Amino-3-iodo-5-(trifluoromethyl)pyridine (CAS 211308-82-6)
- tert-Butyl 3-(((S)-2-amino-N-ethylpropanamido)methyl)pyrrolidine-1-carboxylate (CAS 1354025-21-0)
- 5-((Cyclopropylmethoxy)methyl)furan-2-carbaldehyde (CAS 1399663-77-4)
- Semaglutide impurity 229 (CAS CATO-C4X-2226229)
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