Nalmefene Impurity 28 CAS CATO-C4X-126828
| CAS No. | CATO-C4X-126828 |
| Molecular Formula | C21H27NO3 |
| Molecular Weight | 341.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Nalmefene Impurity 28 (C21H27NO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Nalmefene Impurity 28 (CAS CATO-C4X-126828, C21H27NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H27NO3 |
| Molecular Weight | 341.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Nalmefene Standards
- Nalmefene Impurity 9 (CAS CATO-C4X-12689)
- Nalmefene Impurity 22 (CAS CATO-C4X-126822)
- Nalmefene (CAS 55096-26-9)
- Nalmefene impurity 20 (CAS 738552-29-9)
- Nalmefene Impurity 27 (CAS CATO-C4X-126827)
- Nalmefene Impurity 5 (CAS CATO-C4X-12685)
- Nalmefene Impurity N5 (CAS 91598-83-3)
- Nalmefene Impurity 14 (CAS CATO-C4X-126814)
Recommended Standards
- Bisoprolol Impurity 116 (CAS CATO-C4X-1247116)
- Bisoprolol Impurity 114 (CAS CATO-C4X-1247114)
- Dobutamine Impurity 22 (CAS CATO-C4X-129822)
- Ibuprofen Impurity 77 (CAS CATO-C4X-108277)
- Cariprazine Impurity 14 (CAS 55827-50-4)
- Apixaban Impurity 31 (CAS CATO-C4X-108831)
- Pimobendan Impurity 2 (CAS 2138391-23-6)
- Methyl cis-7,10,13,16-docosatetraenoate (CAS 13487-42-8)
- 4-[(4-Chlorophenyl)methyl]-2-(2,6-difluorophenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile (CAS 672951-30-3)
- N-(3-(benzyloxy)pyridin-2-yl)-4-methylbenzamide (CAS 491867-71-1)
- 3-Chlorophenylglycolic acid (CAS 16273-37-3)
- 1-Benzyl-3-oxopiperidine-4-carbonitrile (CAS 1554341-03-5)
- 1,3-Oxazolidine (CAS 504-76-7)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
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