Nalmefene Impurity 5 CAS CATO-C4X-12685
| CAS No. | CATO-C4X-12685 |
| Molecular Formula | C21H25NO3 |
| Molecular Weight | 339.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Nalmefene Impurity 5 (C21H25NO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a process- or degradation-related impurity, Nalmefene Impurity 5 (CAS CATO-C4X-12685, C21H25NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Nalmefene Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H25NO3 |
| Molecular Weight | 339.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Nalmefene Standards
- Nalmefene impurity 20 (CAS 738552-29-9)
- Nalmefene Impurity 27 (CAS CATO-C4X-126827)
- Nalmefene (CAS 55096-26-9)
- Nalmefene Impurity 22 (CAS CATO-C4X-126822)
- Nalmefene Impurity 28 (CAS CATO-C4X-126828)
- Nalmefene Impurity 9 (CAS CATO-C4X-12689)
- Nalmefene Impurity N5 (CAS 91598-83-3)
- Nalmefene Impurity 14 (CAS CATO-C4X-126814)
Recommended Standards
- Gabapentin Impurity 23 (CAS CATO-C4X-165423)
- Gabapentin Impurity 24 (CAS CATO-C4X-165424)
- Bisoprolol Impurity 92 (CAS CATO-C4X-124792)
- Lidocaine EP Impurity E (CAS 745798-07-6)
- Acalabrutinib Impurity 31 (CAS CATO-C4X-305531)
- Apremilast Impurity 55 (CAS 885268-06-4)
- Conivaptan Impurity 5 (CAS CATO-C4X-13605)
- 2-((2,6-Dichlorobenzyl)oxy)-5-nitrobenzaldehyde (CAS 219539-46-5)
- 2-(4-Allyl-5-morpholino-4H-1,2,4-triazol-3-yl)acetonitrile (CAS 328029-73-8)
- 4-Amino-5-chloro-N',N'-diethyl-2-methoxybenzohydrazide hydrochloride (CAS 1415719-66-2)
- Tetraethyl (fluoromethylene)bis(phosphonate) (CAS 78715-56-7)
- Ethyl (E)-3-(benzylamino)but-2-enoate (CAS 21731-13-5)
- Methyl 2-(isopropylamino)-3-(3-methyl-1h-pyrazol-1-yl)propanoate (CAS 1339059-90-3)
- Semaglutide Impurity 165 (CAS CATO-C4X-2226165)
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