Tacrolimus impurity 71 CAS CATO-C4X-130071
| CAS No. | CATO-C4X-130071 |
| Molecular Formula | C43H69NO12 |
| Molecular Weight | 792.01 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Tacrolimus impurity 71 (CAS CATO-C4X-130071) is a certified pharmaceutical impurity reference standard with the molecular formula C43H69NO12 and a molecular weight of 792.01 g/mol.
Based on its molecular formula C43H69NO12, Tacrolimus impurity 71 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 792.01 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Tacrolimus impurity 71 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C43H69NO12 |
| Molecular Weight | 792.01 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Tacrolimus Standards
- Tacrolimus impurity 44 (CAS 135635-46-0)
- Tacrolimus EP Impurity B (CAS CATO-C4X-130045)
- Tacrolimus Impurity 53 (CAS CATO-C4X-130053)
- Tacrolimus EP Impurity A (CAS 104987-12-4)
- Tacrolimus 31 DMT (CAS 135635-47-1)
- Tacrolimus 15-DMT (CAS 151039-41-7)
- Tacrolimus 31-DMT (CAS 127984-76-3)
- Tacrolimus EP Impurity C (CAS CATO-C4X-130025)
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