Tacrolimus EP Impurity A CAS 104987-12-4
| CAS No. | 104987-12-4 |
| Molecular Formula | C43H69NO12 |
| Molecular Weight | 792.01 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Tacrolimus EP Impurity A (CAS 104987-12-4), a pharmacopoeial impurity reference standard (molecular formula C43H69NO12, MW 792.01 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Tacrolimus EP Impurity A (C43H69NO12) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 792.01 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Tacrolimus EP Impurity A under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C43H69NO12 |
| Molecular Weight | 792.01 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 1 |
Related Tacrolimus Standards
- Tacrolimus impurity 44 (CAS 135635-46-0)
- Tacrolimus EP Impurity B (CAS CATO-C4X-130045)
- Tacrolimus Impurity 53 (CAS CATO-C4X-130053)
- Tacrolimus impurity 71 (CAS CATO-C4X-130071)
- Tacrolimus 31 DMT (CAS 135635-47-1)
- Tacrolimus 15-DMT (CAS 151039-41-7)
- Tacrolimus 31-DMT (CAS 127984-76-3)
- Tacrolimus EP Impurity C (CAS CATO-C4X-130025)
Recommended Standards
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- Isomers of Ascomycin (CAS CATO-C4X-20742)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com