N-Nitroso Nafamostat impurity 124 HCl CAS CATO-C4X-1332124
| CAS No. | CATO-C4X-1332124 |
| Molecular Formula | C11H9N3O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 251.67 g/mol gives N-Nitroso Nafamostat impurity 124 HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies N-Nitroso Nafamostat impurity 124 HCl (CAS CATO-C4X-1332124), a pharmacopoeial impurity reference standard (molecular formula C11H9N3O2HCl, MW 251.67 g/mol) used for the identification and quantification of trace impurities in APIs.
N-Nitroso Nafamostat impurity 124 HCl (C11H9N3O2HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H9N3O2 HCl |
| Molecular Weight | 251.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related N Standards
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Recommended Standards
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- 4-[2-(2-Nitrophenoxy)ethyl]piperidinehydrochloride (CAS 1219982-52-1)
- piperidin-2-ylmethyl N-ethyl-N-methylcarbamate hydrochloride (CAS 1803572-29-3)
- N-(2-Methoxyphenyl)-4-(3-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)piperazine-1-carboxamide (CAS 1070862-25-7)
- 4-(Furan-2-yl)benzaldehyde (CAS 60456-77-1)
- (5-(Pyridin-3-yloxy)furan-2-yl)methanol (CAS 857284-15-2)
- [2-(dimethylamino)phenyl]methanol (CAS 4707-56-6)
- Allo-Thr5-Tirzepatide (CAS CATO-CPTD788934)
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