Nafamostat Impurity 50 CAS CATO-C4X-133250
| CAS No. | CATO-C4X-133250 |
| Molecular Formula | C19H17N5O2 |
| Molecular Weight | 347.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Nafamostat Impurity 50 (CAS CATO-C4X-133250, C19H17N5O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C19H17N5O2, Nafamostat Impurity 50 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 347.37 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Nafamostat Impurity 50 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H17N5O2 |
| Molecular Weight | 347.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Nafamostat Standards
- Nafamostat (CAS 81525-10-2)
- Nafamostat Impurity 5 (CAS CATO-C4X-13325)
- Nafamostat Impurity 62 (CAS 82956-09-0)
- Nafamostat Impurity 64 (CAS 2241024-11-1)
- Nafamostat impurity 81 (CAS CATO-C4X-133281)
- Nafamostat impurity 104 (CAS CATO-C4X-1332104)
- Nafamostat Impurity 2 (CAS CATO-C4X-13322)
- Nafamostat Impurity 4 (CAS CATO-C4X-13324)
Recommended Standards
- Ibrutinib Impurity 42 (CAS CATO-C4X-106442)
- tert-Butyl (2-(dimethylphosphoryl)-4-(methylsulfonyl)phenyl)carbamate (CAS 2903924-13-8)
- PI3K-IN-32 (CAS 371934-59-7)
- Pralatrexate Impurity 2 (CAS 2028268-08-6)
- Rizatriptan Impurity 24 (CAS 119192-11-9)
- Finerenone Impurity 228 (CAS CATO-C4X-2880228)
- Adenosine Impurity 10 (CAS 5987-73-5)
- Imidazo[5,1-b]thiazole-2-carbaldehyde (CAS 268552-79-0)
- 5-(4-Chlorophenethylsulfonyl)-1-phenyl-1H-tetrazole (CAS 1372784-40-1)
- 3-((2-Chlorobenzyl)amino)propanoic acid (CAS 849616-08-6)
- 4-Hydroxy-2-nitrobenzonitrile (CAS 1093203-96-3)
- Tert-butyl 4-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidine-1-carboxylate (CAS 1420816-71-2)
- 1-(10-(3-Aminopropyl)-10H-phenothiazin-2-yl)ethanone (CAS 859045-33-3)
- Fibrinopeptide A, human TFA (CAS 61533-47-9)
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