Nafamostat Impurity 4 CAS CATO-C4X-13324
| CAS No. | CATO-C4X-13324 |
| Molecular Formula | C19H16N4O3 |
| Molecular Weight | 348.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 348.36 g/mol gives Nafamostat Impurity 4 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Nafamostat Impurity 4 (CAS CATO-C4X-13324, C19H16N4O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Nafamostat Impurity 4 (C19H16N4O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 348.36 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Nafamostat Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H16N4O3 |
| Molecular Weight | 348.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Nafamostat Standards
- Nafamostat impurity 104 (CAS CATO-C4X-1332104)
- Nafamostat Impurity 2 (CAS CATO-C4X-13322)
- Nafamostat Impurity 3 (CAS CATO-C4X-13323)
- Nafamostat impurity 88 (CAS 2810790-31-7)
- Nafamostat (CAS 81525-10-2)
- Nafamostat Impurity 5 (CAS CATO-C4X-13325)
- Nafamostat Impurity 50 (CAS CATO-C4X-133250)
- Nafamostat Impurity 62 (CAS 82956-09-0)
Recommended Standards
- Pralatrexate Impurity 4 (CAS 146464-93-9)
- Finerenone Impurity 94 (CAS CATO-C4X-288094)
- Ilaprazole Impurity 31 (CAS 2285346-38-3)
- Finerenone Impurity 95 (CAS CATO-C4X-288095)
- Entecavir Impurity 85 (CAS CATO-C4X-107785)
- Tofacitinib Impurity 103 (CAS CATO-C4X-1079103)
- Palbociclib Impurity 87 HCl (CAS 2174002-29-8(free base))
- N-CYclopropyl-3-hydroxybenzene-1-sulfonamide (CAS 1082398-44-4)
- 1-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-1H-pyrazol-3-amine (CAS 1006434-99-6)
- Piperidin-4-yl(pyridin-3-yl)methanone (CAS 747403-13-0)
- (2R,10AS)-2,7-dimethyl-1,2,3,5,10,10a-hexahydrodipyrrolo[1,2-a:1',2'-d]pyrazine (CAS 202721-35-5)
- Cefcapene Impurity 40 (CAS CATO-C4X-182440)
- (2S)-2-(4-bromophenoxy)propanoic acid (CAS 37819-43-5)
- Tau Peptide (268-282) trifluoroacetate salt (CAS 330456-37-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com