Nafamostat Impurity 5 CAS CATO-C4X-13325
| CAS No. | CATO-C4X-13325 |
| Molecular Formula | C19H17N5O2 |
| Molecular Weight | 347.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Nafamostat Impurity 5 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Nafamostat Impurity 5 (CAS CATO-C4X-13325), a pharmacopoeial impurity reference standard (molecular formula C19H17N5O2, MW 347.37 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C19H17N5O2, Nafamostat Impurity 5 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 347.37 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H17N5O2 |
| Molecular Weight | 347.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Nafamostat Standards
- Nafamostat (CAS 81525-10-2)
- Nafamostat Impurity 50 (CAS CATO-C4X-133250)
- Nafamostat Impurity 62 (CAS 82956-09-0)
- Nafamostat Impurity 64 (CAS 2241024-11-1)
- Nafamostat impurity 81 (CAS CATO-C4X-133281)
- Nafamostat impurity 104 (CAS CATO-C4X-1332104)
- Nafamostat Impurity 2 (CAS CATO-C4X-13322)
- Nafamostat Impurity 4 (CAS CATO-C4X-13324)
Recommended Standards
- Ibrutinib Impurity 42 (CAS CATO-C4X-106442)
- tert-Butyl (2-(dimethylphosphoryl)-4-(methylsulfonyl)phenyl)carbamate (CAS 2903924-13-8)
- PI3K-IN-32 (CAS 371934-59-7)
- N1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-N2-(3-(2-oxopyrrolidin-1-yl)propyl)oxalamide (CAS 900001-01-6)
- Nemonoxacin impurity 113 (CAS CATO-C4X-3128113)
- Fasudil Impurity 45 (CAS CATO-C4X-136545)
- Epalrestat impurity 49 (CAS CATO-C4X-223649)
- Sarpogrelate Impurity 13 (CAS CATO-C4X-291313)
- Ethyl(4-fluoro-3-methylphenyl)sulfane (CAS 252555-34-3)
- (5-Fluoro-2-methoxypyridin-3-yl)methanamine (CAS 874823-00-4)
- 1,2-Dimethylimidazole (CAS 1739-84-0)
- Fmoc-3-Abz-OH (CAS 185116-42-1)
- 2-Chloro-4-(methoxymethoxy)phenylboronic acid (CAS 1135992-31-2)
- Acetyl Tetrapeptide-11 (CAS 928006-88-6)
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