Sertraline Impurity 61 CAS CATO-C4X-134461
| CAS No. | CATO-C4X-134461 |
| Molecular Formula | C21H26ClNO |
| Molecular Weight | 343.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Sertraline Impurity 61 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Sertraline Impurity 61 (CAS CATO-C4X-134461), a pharmacopoeial impurity reference standard (molecular formula C21H26ClNO, MW 343.89 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Sertraline Impurity 61 (C21H26ClNO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 343.89 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Sertraline Impurity 61 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H26ClNO |
| Molecular Weight | 343.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Sertraline Standards
- Sertraline Impurity 60 (CAS CATO-C4X-134460)
- Sertraline Impurity 62 (CAS CATO-C4X-134462)
- Sertraline Impurity 63 (CAS CATO-C4X-134463)
- Sertraline impurity 44 (CAS CATO-C4X-134444)
- Sertraline Acetamide (CAS 1097616-52-8)
- Sertraline Impurity 55 (CAS 147250-57-5)
- Sertraline N-Oxide (CAS 209473-00-7)
- Sertraline RC 16 (CAS 674768-11-7)
Recommended Standards
- rac-Clemastine Fumarate EP Impurity B (CAS 61771-18-4)
- 5-(4-Butylphenyl)-6-chloro-N-cyclopentyl-2-methylpyrimidin-4-amine (CAS 917895-67-1)
- Clemastine Impurity 15 (CAS CATO-C4X-183715)
- 4,5-Diiodo-1H-pyrrole-2-carbonitrile (CAS 51148-01-7)
- Lenvatinib Impurity 99 (CAS 756488-67-2)
- Candesartan Impurity 6 (CAS CATO-C4X-15726)
- Aprepitant Impurity 11 (CAS CATO-C4X-114111)
- 2-[(3,4-Dichlorobenzyl)oxy]benzaldehyde (CAS 194802-96-5)
- Avibactam Impurity 160 (CAS CATO-C4X-1348160)
- N-(5-(Pyridin-3-yl)-1,3,4-thiadiazol-2-yl)cyclobutanecarboxamide (CAS 603073-26-3)
- 4-Ethoxy-1-phenyl-1h-pyrazole-3-carboxylic acid (CAS 1152603-09-2)
- tert-Butyl 2-phenyl-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate (CAS 1400642-62-7)
- 2-((4-Fluorobenzyl)amino)-4-(4-isopropylphenyl)-4-oxobutanoic acid (CAS 1024697-65-1)
- Semaglutide impurity 271 (CAS CATO-C4X-2226271)
Why CATO?
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