Fluticasone Impurity 63 CAS CATO-C4X-165063
| CAS No. | CATO-C4X-165063 |
| Molecular Formula | C22H30F2O5 |
| Molecular Weight | 412.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Fluticasone Impurity 63 (CAS CATO-C4X-165063), a pharmacopoeial impurity reference standard (molecular formula C22H30F2O5, MW 412.47 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Fluticasone Impurity 63 (C22H30F2O5) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 412.47 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H30F2O5 |
| Molecular Weight | 412.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Fluticasone Standards
- Fluticasone Impurity 45 (CAS 80473-92-3)
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- Fluticasone Impurity 57 (CAS CATO-C4X-165057)
- Fluticasone Impurity 58 (CAS CATO-C4X-165058)
- Fluticasone Impurity 61 (CAS CATO-C4X-165061)
- Fluticasone Impurity 67 (CAS CATO-C4X-165067)
- Fluticasone Impurity 101 (CAS CATO-C4X-1650101)
- Fluticasone Impurity 49 (CAS CATO-C4X-165049)
Recommended Standards
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- Voriconazole Impurity 11 (CAS 618109-05-0)
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