Paricalcitol lmpurity 41 CAS CATO-C4X-138741

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-138741
Molecular FormulaC32H51O3PSi2
Molecular Weight570.89 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Paricalcitol lmpurity 41 CAS CATO-C4X-138741 chemical structure

Description

Paricalcitol lmpurity 41 (C32H51O3PSi2) contains a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Paricalcitol lmpurity 41 (CAS CATO-C4X-138741) is a certified pharmaceutical impurity reference standard with the molecular formula C32H51O3PSi2 and a molecular weight of 570.89 g/mol.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC32H51O3PSi2
Molecular Weight570.89 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity>95%
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present

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