Paricalcitol lmpurity 40 CAS CATO-C4X-138740
| CAS No. | CATO-C4X-138740 |
| Molecular Formula | 2*C26H37O3PSi |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Paricalcitol lmpurity 40 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Paricalcitol lmpurity 40 (CAS CATO-C4X-138740, C26H37O3PSi) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Paricalcitol lmpurity 40 (C26H37O3PSi) is characterized by a steroid core, a phosphonate group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | 2*C26H37O3PSi |
| Molecular Weight | 456.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Paricalcitol Standards
- Paricalcitol Impurity 15 (CAS 100858-25-1)
- Paricalcitol Impurity 16 (CAS 100858-26-2)
- Paricalcitol Impurity 37 (CAS 1154606-20-8)
- Paricalcitol Impurity 22 (CAS 1186587-44-9)
- Paricalcitol lmpurity 42 (CAS 1186587-53-0)
- Paricalcitol Impurity 11 (CAS 1227926-70-6)
- Paricalcitol 25-β-D-Glucuronide (CAS 1260588-15-5)
- Paricalcitol Impurity 12 (CAS 1263504-45-5)
Recommended Standards
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- N-cyclopropyl-4-methyl-3-nitrobenzamide (CAS 303133-89-3)
- Neuropeptide Y (18-36) (CAS 114495-97-5)
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