Metoclopramide impurity 72 CAS CATO-C4X-141572
| CAS No. | CATO-C4X-141572 |
| Molecular Formula | C28H45N6O5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Metoclopramide impurity 72.
As a process- or degradation-related impurity, Metoclopramide impurity 72 (CAS CATO-C4X-141572, C28H45N6O5Cl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C28H45N6O5Cl, Metoclopramide impurity 72 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 581.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H45N6O5 Cl |
| Molecular Weight | 581.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Metoclopramide Standards
- Metoclopramide EP Impurity E (CAS 100-36-7)
- Metoclopramide Impurity 68 (CAS 101385-94-8)
- Metoclopramide impurity 70 (CAS 102313-35-9)
- Metoclopramide Impurity 11 (CAS 111049-74-2)
- Metoclopramide-related Impurity (CAS 121048-67-7)
- Metoclopramide-d3 (CAS 1216522-89-2)
- Metoclopramide impurity 60 (CAS 1242047-97-7)
- Metoclopramide Impurity 83 (CAS 1242047-99-9)
Recommended Standards
- Atomoxetine Impurity N15 (CAS 1643684-02-9)
- Articaine EP Impurity C (CAS CATO-C4X-19124)
- Moxifloxacin Impurity 67 (CAS 151213-39-7 (free base))
- LDN 212320 (CAS 894002-50-7)
- 4-(1h-1,2,4-Triazol-1-yl)butan-1-ol (CAS 1153126-19-2)
- 1-(2-Methoxyphenyl)pentane-1,3-dione (CAS 78589-97-6)
- 4-Chloro-N-(1-(4-ethyl-5-(methylthio)-4H-1,2,4-triazol-3-yl)ethyl)benzenesulfonamide (CAS 338954-07-7)
- 2-Butoxy-2-oxoethyl butyl phthalate (CAS 85-70-1)
- 4-(3,4-Dimethylphenyl)butan-2-ol (CAS 827299-49-0)
- Acetyl Tripeptide-1 (CAS 350595-76-5)
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