Domperidone Impurity 41 CAS CATO-C4X-142041

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-142041
Molecular FormulaC20H20Cl2N4O6
Molecular Weight483.30 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Domperidone Impurity 41 CAS CATO-C4X-142041 chemical structure

Description

The occurrence of Domperidone Impurity 41 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Domperidone Impurity 41 (CAS CATO-C4X-142041), a pharmacopoeial impurity reference standard (molecular formula C20H20Cl2N4O6, MW 483.30 g/mol) used for the identification and quantification of trace impurities in APIs.

Domperidone Impurity 41 (C20H20Cl2N4O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Domperidone Impurity 41 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC20H20Cl2N4O6
Molecular Weight483.30 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity≥95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentCl-containing
Nitrogen Atoms4

Related Domperidone Standards

Recommended Standards

Why CATO?