N-Nitroso Desloratadine Impurity A CAS CATO-C4X-143056

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-143056
Molecular FormulaC19H19N3O
Molecular Weight305.37 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

N-Nitroso Desloratadine Impurity A CAS CATO-C4X-143056 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 305.37 g/mol gives N-Nitroso Desloratadine Impurity A distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

N-Nitroso Desloratadine Impurity A (CAS CATO-C4X-143056) is a certified pharmaceutical impurity reference standard with the molecular formula C19H19N3O and a molecular weight of 305.37 g/mol.

Based on its molecular formula C19H19N3O, N-Nitroso Desloratadine Impurity A contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 305.37 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC19H19N3O
Molecular Weight305.37 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms3

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