Flumazenil Impurity 21 CAS CATO-C4X-143221
| CAS No. | CATO-C4X-143221 |
| Molecular Formula | C14H16FN3O3 |
| Molecular Weight | 293.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Flumazenil Impurity 21 (C14H16FN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Flumazenil Impurity 21 (CAS CATO-C4X-143221), a pharmacopoeial impurity reference standard (molecular formula C14H16FN3O3, MW 293.29 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H16FN3O3 |
| Molecular Weight | 293.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Flumazenil Standards
- Flumazenil Impurity 14 (CAS 1291916-17-0)
- Flumazenil (N-[11C]Methyl) EP Impurity A (CAS 79089-72-8)
- Flumazenil Impurity 8 (CAS 78755-82-5)
- Flumazenil EP Impurity E (CAS 78756-03-3)
- Flumazenil EP Impurity B (CAS 131666-45-0)
- Flumazenil Impurity 12 (CAS CATO-C4X-143212)
- Flumazenil-D5 (CAS 2700278-14-2)
- Flumazenil (CAS 78755-81-4)
Recommended Standards
- Paroxetine Impurity 56 (CAS 202534-94-9)
- Sulbactam Impurity 16 (CAS CATO-C4X-175616)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com