Venlafaxine Impurity 12 CAS CATO-C4X-143412
| CAS No. | CATO-C4X-143412 |
| Molecular Formula | C20H29NO5 |
| Molecular Weight | 363.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Venlafaxine Impurity 12 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Venlafaxine Impurity 12 (CAS CATO-C4X-143412), a pharmacopoeial impurity reference standard (molecular formula C20H29NO5, MW 363.45 g/mol) used for the identification and quantification of trace impurities in APIs.
Venlafaxine Impurity 12 (C20H29NO5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H29NO5 |
| Molecular Weight | 363.45 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Venlafaxine Standards
- Venlafaxine Impurity 11 (CAS CATO-C4X-143411)
- Venlafaxine impurity 56 (CAS 916918-81-5)
- Venlafaxine Impurity 13 (CAS 1346601-21-5)
- Venlafaxine Impurity 57 (CAS 93413-61-7)
- Venlafaxine Impurity 70 (CAS CATO-C4X-143470)
- Venlafaxine EP Impurity H（Mixture of Enantiomers） (CAS 1329795-88-1)
- Venlafaxine Impurity 68 (CAS CATO-C4X-143468)
- Venlafaxine Impurity N2 (CAS 1346601-14-6)
Recommended Standards
- Brivaracetam Impurity 118 (CAS CATO-C4X-2007118)
- Roxatidine Impurity 81 (CAS CATO-C4X-121381)
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- Terbutaline impurity 106 (CAS CATO-C4X-1183106)
- Apixaban Impurity 69 (CAS CATO-C4X-108869)
- Sitafloxacin dimer Impurity 67 HCl (CAS CATO-C4X-115567)
- Roflumilast Impurity 52 (CAS CATO-C4X-108452)
- 3-(2-Bromophenyl)-9-phenyl-9H-carbazole (CAS 1190100-35-6)
- 2-Methylimidazo[1,2-a]pyridine-3-carboxylic acid hydrochloride (CAS 1448074-95-0)
- 1-(Triphenylphosphoranylidene)butan-2-one (CAS 19753-66-3)
- methyl 2-amino-4-chloro-1,3-benzothiazole-6-carboxylate (CAS 1427425-98-6)
- 2-Chloro-5-hydrazinylbenzoic acid (CAS 327092-95-5)
- Phenyl chlorothioformate (CAS 13464-19-2)
- Liraglutide Impurity 18 TFA Salt (CAS CATO-C4X-199218)
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