Venlafaxine Impurity N2 CAS 1346601-14-6
| CAS No. | 1346601-14-6 |
| Molecular Formula | C25H35NO3 |
| Molecular Weight | 397.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Venlafaxine Impurity N2 (CAS 1346601-14-6) is a certified pharmaceutical impurity reference standard with the molecular formula C25H35NO3 and a molecular weight of 397.56 g/mol.
Structurally, Venlafaxine Impurity N2 (C25H35NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 397.56 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Venlafaxine Impurity N2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H35NO3 |
| Molecular Weight | 397.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Related Venlafaxine Standards
- Venlafaxine Impurity 68 (CAS CATO-C4X-143468)
- Venlafaxine EP Impurity H（Mixture of Enantiomers） (CAS 1329795-88-1)
- Venlafaxine Impurity 70 (CAS CATO-C4X-143470)
- Venlafaxine Impurity 76 (CAS CATO-C4X-143476)
- Venlafaxine impurity 56 (CAS 916918-81-5)
- Venlafaxine Impurity 11 (CAS CATO-C4X-143411)
- Venlafaxine Impurity 12 (CAS CATO-C4X-143412)
- Venlafaxine Impurity 13 (CAS 1346601-21-5)
Recommended Standards
- N-Cyclohexyl-2-((5-(3-cyclohexylureido)-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 898461-94-4)
- (5Z,8Z,11Z)-N-(Methylsulfonyl)-13-(3-pentyloxiran-2-yl)trideca-5,8,11-trienamide (CAS 218461-97-3)
- Norfloxacin Impurity 51 (CAS CATO-C4X-146851)
- 1-((1R,2R)-2-(Dimethylamino)cyclohexyl)-3-((1R,2R)-2-hydroxy-1,2-diphenylethyl)thiourea (CAS 1046493-33-7)
- Buspirone EP Impurity J Oxalate (CAS 2726492-73-3)
- Thiamine Impurity 33 (CAS 861031-76-7)
- Vericiguat Impurity 30 (CAS CATO-C4X-289630)
- 1-Chloroisoquinolin-4-amine (CAS 1260799-38-9)
- (4-Chlorophenyl)[4-(3-piperidinyloxy)phenyl]-methanone (CAS 946759-28-0)
- 2-((4-Chlorobenzyl)thio)-4-(3,4-dimethoxyphenyl)-6-(p-tolyl)nicotinonitrile (CAS 337925-08-3)
- Ethyl 3-bromo-7-methylimidazo[1,2-a]pyridine-2-carboxylate hydrobromide (CAS 1332588-44-9)
- 1-(2,5-Dichloro-4-nitrophenyl)-1H-pyrrole (CAS 175135-54-3)
- 1-(4-Amino-2-bromopyridin-3-yl)ethanone (CAS 1393573-65-3)
- Peptide 442 (CAS CATO-CPTD788442)
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