Venlafaxine Impurity 71 CAS CATO-C4X-143471
| CAS No. | CATO-C4X-143471 |
| Molecular Formula | C16H24ClNO |
| Molecular Weight | 281.82 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Venlafaxine Impurity 71 (CAS CATO-C4X-143471, C16H24ClNO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Venlafaxine Impurity 71 (C16H24ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H24ClNO |
| Molecular Weight | 281.82 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Venlafaxine Standards
- Venlafaxine D4 (CAS 93413-69-5(Unlabelled))
- Venlafaxine Impurity 27 (CAS 940297-06-3)
- Venlafaxine Impurity 15 (CAS 1021933-95-8)
- Venlafaxine Impurity 38 (CAS 93413-44-6)
- Venlafaxine Impurity 39 (CAS 93413-46-8)
- Venlafaxine Impurity 80 (CAS CATO-C4X-143480)
- Venlafaxine EP Impurity E (CAS 93413-70-8)
- Venlafaxine Impurity 35 (CAS CATO-C4X-143435)
Recommended Standards
- 2-Chloro-N-(3,5-di-tert-butylphenyl)acetamide (CAS 287198-03-2)
- Trazodone Impurity 36 (CAS CATO-C4X-177236)
- 2-Chloro-4-undecanoylpyridine (CAS 898784-78-6)
- 1,2-Diiodoethane 624-73-7 D1025 Ethylene Diiodide Ethylene Iodide (CAS 624-73-7)
- Mosapride Impurity 41 (CAS CATO-C4X-104441)
- Avatrombopag Impurity 140 (CAS CATO-C4X-2234140)
- Erlotinib Impurity 113 (CAS 587-02-0)
- 2-(2-Naphthoyl)benzoic acid (CAS 38119-03-8)
- trans-(4-Propylcyclohexyl)cyclohex-1-enylboronic acid (CAS 1256346-32-3)
- Dabigatran Impurity 84 (CAS 873-74-5)
- Ethyl 4-chlorothieno[2,3-c]pyridine-2-carboxylate (CAS 2089292-26-0)
- 1-((4-Ethylmorpholin-2-yl)methyl)-1h-1,2,4-triazol-3-amine (CAS 1523098-67-0)
- 5-((1H-Indol-3-yl)methyl)-2-(methylamino)thiazol-4(5H)-one (CAS 61492-52-2)
- Peptide YY (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 81858-94-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com