Trazodone Impurity 36 CAS CATO-C4X-177236
| CAS No. | CATO-C4X-177236 |
| Molecular Formula | C15H24ClN3 |
| Molecular Weight | 281.82 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 281.82 g/mol gives Trazodone Impurity 36 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Trazodone Impurity 36 (CAS CATO-C4X-177236) is a certified pharmaceutical impurity reference standard with the molecular formula C15H24ClN3 and a molecular weight of 281.82 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Trazodone Impurity 36 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 281.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Trazodone Impurity 36 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H24ClN3 |
| Molecular Weight | 281.82 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Trazodone Standards
- Trazodone impurity 77 (CAS 1799917-53-5)
- Trazodone impurity 54 (CAS CATO-C4X-177254)
- Trazodone Impurity 66 (CAS CATO-C4X-177266)
- Trazodone Impurity 73 (CAS 6323-14-4)
- Trazodone Impurity 89 (CAS CATO-C4X-177289)
- Trazodone Impurity N16 (CAS 39577-43-0)
- Trazodone Impurity 100 (CAS CATO-C4X-1772100)
- Trazodone Impurity 103 (CAS CATO-C4X-1772103)
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