Erlotinib Impurity 113 CAS 587-02-0
| CAS No. | 587-02-0 |
| Molecular Formula | C8H11N |
| Molecular Weight | 121.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Erlotinib Impurity 113 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Erlotinib Impurity 113 (CAS 587-02-0, C8H11N) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C8H11N, Erlotinib Impurity 113 contains a nitrogen-containing heterocyclic scaffold, a nitrile group; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 121.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Erlotinib Impurity 113 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H11N |
| Molecular Weight | 121.18 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Erlotinib Standards
- Erlotinib Impurity 122 (CAS 1709-44-0)
- Erlotinib Impurity 116 (CAS 15411-43-5)
- Erlotinib Impurity 114 (CAS 14235-81-5)
- Erlotinib Impurity 115 (CAS 52670-38-9)
- Erlotinib Impurity 120 (CAS 54060-30-9)
- Erlotinib Impurity 24 (CAS 134690-40-7)
- Erlotinib Impurity 112 (CAS 99-03-6)
- Erlotinib Impurity 117 (CAS 139-85-5)
Recommended Standards
- DL-1-Phenylethylamine (CAS 618-36-0)
- Esomeprazole Impurity 111 (CAS 695-98-7)
- N-Methylbenzylamine (CAS 103-67-3)
- Nicotinic Acid EP Impurity C (CAS 104-90-5)
- Sitagliptin Impurity 15 (CAS 1217809-78-3)
- Ivacaftor Impurity 6 (CAS 873054-39-8)
- Betamethasone impurity 95 (CAS 1815577-58-2)
- 951-05-3 Phenanthrene, 9-(chloromethyl)- 9-(Chloromethyl)phenanthrene NSC 82368 (CAS 951-05-3)
- Hydroxychloroquine Impurity 18 (CAS 140-80-7)
- 2-(1h-Indol-3-yl)-N,N-dimethylacetamide (CAS 91566-04-0)
- Ethyl 4-(4-aminophenyl)benzoate, HCl (CAS 1355247-33-4)
- Ethyl 4-(allylamino)-6-nitroquinoline-3-carboxylate (CAS 478248-30-5)
- 2-Methoxy-d3-benzaldehyde (CAS 56248-49-8)
- Tirzepatide Impurity 46 (CAS CATO-C4X-324046)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com