Betamethasone impurity 62 CAS CATO-C4X-143762
| CAS No. | CATO-C4X-143762 |
| Molecular Formula | C23H29FO6 |
| Molecular Weight | 420.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Betamethasone impurity 62 (CAS CATO-C4X-143762) is a certified pharmaceutical impurity reference standard with the molecular formula C23H29FO6 and a molecular weight of 420.47 g/mol.
The molecular framework of Betamethasone impurity 62 (C23H29FO6) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H29FO6 |
| Molecular Weight | 420.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Betamethasone Standards
- Betamethasone Impurity 116 (CAS CATO-C4X-1437116)
- Betamethasone Impurity 87 (CAS 1549-35-5)
- Betamethasone Impurity 127 (CAS CATO-C4X-1437127)
- Betamethasone Acetate EP Impurity D (CAS 912-38-9)
- Betamethasone impurity 105 (CAS CATO-C4X-1437105)
- Betamethasone impurity 51 (CAS 1184871-61-1)
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Recommended Standards
- Flunisolide-17- Acid (CAS 75575-02-9)
- Triamcinolone Impurity 10 (CAS 3800-28-0)
- Fludrocortisone Impurity 1 (CAS 564-57-8)
- Dexamethasone impurity 79 (CAS CATO-C4X-116579)
- Revefenacin Impurity 17 (CAS 96053-48-4)
- Relugolix Impurity 87 (CAS CATO-C4X-242987)
- Procaterol Impurity 27 (CAS CATO-C4X-181027)
- N-(2-methoxy-5-nitrophenyl)-N-(methylsulfonyl)glycine (CAS 718603-61-3)
- 2-(Aminomethyl)-3-bromo-4-(difluoromethyl)-6-fluoropyridine (CAS 1804635-92-4)
- tert-Butyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxa-borolan-2-yl) phenyl carbonate (CAS 480438-74-2)
- (2R,3S)-3-((tert-Butoxycarbonyl)amino)oxetane-2-carboxylic acid (CAS 2012574-97-7)
- 4-Bromo-7-(trifluoromethoxy)quinoline (CAS 1189105-57-4)
- 3,3-Dimethyl-2-oxobutyl 2-fluorobenzoate (CAS 474945-57-8)
- Liraglutide(14-22)TFA Salt (CAS CATO-C4X-199212)
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