Betamethasone impurity 60 CAS CATO-C4X-143760
| CAS No. | CATO-C4X-143760 |
| Molecular Formula | C22H27O8P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Betamethasone impurity 60 (CAS CATO-C4X-143760), a pharmacopoeial impurity reference standard (molecular formula C22H27O8PNa, MW 473.41 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C22H27O8PNa, Betamethasone impurity 60 contains a flavonoid core, a phosphate ester group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 473.41 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H27O8P 2*Na |
| Molecular Weight | 473.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Betamethasone Standards
- Betamethasone Cyclic 17,21-(Ethyl Orthopropionate) (CAS 1062-09-5)
- Betamethasone impurity 91 (CAS 114488-14-1)
- Betamethasone impurity 97 (CAS 1150311-95-7)
- Betamethasone Impurity N22 (CAS 116522-68-0)
- Betamethasone Impurity 27 (CAS 116846-77-6)
- Betamethasone impurity 51 (CAS 1184871-61-1)
- Betamethasone Dipropionate EP Impurity G (CAS 1186048-33-8)
- Betamethasone Dipropionate impurity 02 (CAS 1186048-34-9)
Recommended Standards
- Nemonoxacin Impurity 118 (CAS CATO-C4X-3128118)
- Mesalamine Impurity 41 (CAS CATO-C4X-132441)
- Terbutaline impurity 131 (CAS CATO-C4X-1183131)
- [1,4-Bipiperidine]-1-carbonyl-d (CAS 718613-18-4)
- 4-Cyano-5-(2-cyanoacetamido)-N,N-diethyl-3-methylthiophene-2-carboxamide (CAS 581780-63-4)
- [1-methyl-6-(trifluoromethyl)piperidin-3-yl]methyl 4-methylbenzene-1-sulfonate (CAS 1637310-83-8)
- Ethyl trans-3-hydroxy-1-methylcyclobutanecarboxylate (CAS 1408074-59-8)
- 9-Amino-1,2,3,4-tetrahydroacridin-1-ol-d3 (CAS 1219806-47-9)
- Aztreonam impurity 100 (CAS CATO-C4X-1522100)
- Semaglutide impurity 215 (CAS CATO-C4X-2226215)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com