Triamcinolone Impurity 10 CAS 3800-28-0
| CAS No. | 3800-28-0 |
| Molecular Formula | C23H29FO6 |
| Molecular Weight | 420.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Triamcinolone Impurity 10 (CAS 3800-28-0) is a certified pharmaceutical impurity reference standard with the molecular formula C23H29FO6 and a molecular weight of 420.47 g/mol.
The molecular framework of Triamcinolone Impurity 10 (C23H29FO6) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C23H29FO6 |
| Molecular Weight | 420.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
Related Triamcinolone Standards
- Triamcinolone Acetonide Impurity N2 (CAS 1893-84-1)
- Triamcinolone Acetonide EP Impurity B (CAS 1260149-96-9)
- Triamcinolone Acetonide (CAS 76-25-5)
- Triamcinolone EP Impurity B (CAS 3859-65-2)
- Triamcinolone Acetonide EP Impurity E (CAS 1524-86-3)
- Triamcinolone Acetonide-d6 (CAS 352431-33-5)
- Triamcinolone EP Impurity C (CAS 337-02-0)
- Triamcinolone Acetonide Impurity 44 (CAS CATO-C4X-132644)
Recommended Standards
- Dexamethasone impurity 79 (CAS CATO-C4X-116579)
- Betamethasone Impurity 116 (CAS CATO-C4X-1437116)
- Decitabine Impurity 48 (CAS CATO-C4X-113748)
- Betamethasone impurity 62 (CAS CATO-C4X-143762)
- Perospirone Impurity 29 (CAS 205673-80-9)
- Daptomycin Impurity 39 (CAS CATO-C4X-137839)
- Pioglitazone impurity 30 (CAS 1229114-66-2)
- Deferasirox-d4 (CAS 1133425-75-8)
- Thymolphthalein monophosphate2-amino-2-methyl-1,3-propanediolsalt (CAS 52279-66-0)
- Cts-1027 (CAS 193022-04-7)
- 4-(4-Carboxy-3-fluorophenyl)-2-fluorophenol (CAS 1261981-84-3)
- 2-Bromocycloheptanone (CAS 766-65-4)
- Paracetamol EP Impurity J (CAS 539-03-7)
- Semaglutide impurity 86 (CAS CATO-C4X-152686)
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