Deferasirox Impurity 20 CAS CATO-C4X-143820
| CAS No. | CATO-C4X-143820 |
| Molecular Formula | C8H8N2O3 |
| Molecular Weight | 180.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Deferasirox Impurity 20 is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Deferasirox Impurity 20 (CAS CATO-C4X-143820) is a certified pharmaceutical impurity reference standard with the molecular formula C8H8N2O3 and a molecular weight of 180.16 g/mol.
Deferasirox Impurity 20 (C8H8N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Deferasirox Impurity 20 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8N2O3 |
| Molecular Weight | 180.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Deferasirox Standards
- Deferasirox Impurity 12 (CAS 14685-90-6)
- Deferasirox EP Impurity F (CAS 619-67-0)
- Deferasirox Impurity 21 (CAS CATO-C4X-143821)
- Deferasirox EP Impurity B (CAS 1218-69-5)
- Deferasirox Impurity 15 (CAS CATO-C4X-143815)
- Deferasirox EP Impurity A (CAS 1972-71-0)
- Deferasirox Impurity 17 (CAS 155528-92-0)
- Deferasirox Impurity 11 (CAS 586-91-4)
Recommended Standards
- Aspirin Impurity 12 (CAS 13110-96-8)
- Mycophenolate Impurity 20 (CAS 27979-57-3)
- Nafamostat Impurity 15 (CAS 6306-25-8)
- Doxazosin EP Impurity A (CAS 3663-80-7)
- Bromhexine Impurity 47 (CAS CATO-C4X-106047)
- Semaglutide impurity 57 (CAS 2773558-06-6)
- Flurbiprofen Impurity 143 (CAS CATO-C4X-1444143)
- Dimethyl(2-oxo-2-phenylethyl)sulfonium bromide (CAS 5667-47-0)
- (R)-3-(Phenylsulfonyl)pyrrolidine (CAS 1268521-39-6)
- 3,5-Dimethyl-1-(2-methyl-allyl)-1H-pyrazole-4-carbaldehyde (CAS 1004365-13-2)
- Aspartame EP Impurity A (CAS 5262-10-2)
- 2-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]-3-phenylacrylonitrile (CAS 332045-71-3)
- Risperidone EP Impurity E (CAS 1346602-28-5)
- Tirzepatide Impurity 23 X TFA Salt (CAS CATO-C4X-324023)
Why CATO?
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