Tizanidine Impurity 43 CAS CATO-C4X-144543
| CAS No. | CATO-C4X-144543 |
| Molecular Formula | C11H12ClN5S |
| Molecular Weight | 281.76 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Tizanidine Impurity 43 (CAS CATO-C4X-144543, C11H12ClN5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution, Tizanidine Impurity 43 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 281.76 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12ClN5S |
| Molecular Weight | 281.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Tizanidine Standards
- Tizanidine impurity 24 (CAS CATO-C4X-144524)
- Tizanidine Nitroso Impurity 13 (CAS CATO-C4X-144513)
- Tizanidine Impurity 38 (CAS CATO-C4X-144538)
- Tizanidine Impurity 45 (CAS CATO-C4X-144545)
- Tizanidine Impurity 63 (CAS CATO-C4X-144563)
- Tizanidine impurity 30 (CAS CATO-C4X-144530)
- Tizanidine impurity 027 (CAS 5391-42-4)
- Tizanidine impurity 21 (CAS CATO-C4X-144521)
Recommended Standards
- 338982-17-5 ethyl 2-(2-chlorophenyl)-4-methyl-1,3-thiazole-5-carboxylate DTXSID70377059 (CAS 338982-17-5)
- (3S,4R)-1-(tert-butyl)-4-(4-chlorophenyl)pyrrolidine-3-carboxylic acid (CAS 1002728-89-3)
- N-[2-(4-Chlorophenoxy)ethyl]thiophene-2-carboxamide (CAS 311316-42-4)
- 4-((2-(Chloromethyl)thiophen-3-yl)sulfonyl)morpholine (CAS 1030431-21-0)
- Carbocisteine Impurity 45 (CAS CATO-C4X-201045)
- Bupropion Impurity 03 (CAS 2763780-10-3)
- Mianserin impurity 39 (CAS CATO-C4X-136939)
- 6-(Trifluoromethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 189940-04-3)
- 2-[3-(aminomethyl)phenoxy]-n-cyclopropylacetamide hydrochloride (CAS 1221723-43-8)
- N-Isopropyl-N-(pyrrolidin-2-ylmethyl)acetamide (CAS 1353987-02-6)
- 2-Chloro-8-methylquinoline (CAS 4225-85-8)
- Progesterone Impurity N7 (CAS 80699-76-9)
- 2,4,7-Trichloro-5-nitro-9H-fluorene (CAS 91821-44-2)
- (2S)-2-amino-4-(hydroxymethylphosphinyl)butanoyl-L-alanyl-L-alanine (2S)-2-amino-4-[hydroxy(methyl)phosphinoyl]butyryl-L-alanyl-L-alanine 2-Amino-4-(methylphosphino)butyrylalanylalanine 35597-43-4 Antibiotic SF 1293 Bialaphos CHEBI:3088 L-phosphinothricyl-L-alanyl-L-alanine N-{(2S)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoyl}-L-alanyl-L-alanine PTT Phosphinothricylalanylalanine bilanafos gamma-(Hydroxymethylphosphinyl)-L-alpha-aminobutyryl-L-alanyl-L-alanine phosphinothricin tripeptide (CAS 35597-43-4)
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