Tizanidine impurity 24 CAS CATO-C4X-144524
| CAS No. | CATO-C4X-144524 |
| Molecular Formula | C11H11ClN4O3 |
| Molecular Weight | 282.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Tizanidine impurity 24 (CAS CATO-C4X-144524) is a certified pharmaceutical impurity reference standard with the molecular formula C11H11ClN4O3 and a molecular weight of 282.68 g/mol.
The molecular framework of Tizanidine impurity 24 (C11H11ClN4O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H11ClN4O3 |
| Molecular Weight | 282.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Tizanidine Standards
- Tizanidine Nitroso Impurity 13 (CAS CATO-C4X-144513)
- Tizanidine Impurity 38 (CAS CATO-C4X-144538)
- Tizanidine Impurity 45 (CAS CATO-C4X-144545)
- Tizanidine Impurity 63 (CAS CATO-C4X-144563)
- Tizanidine Impurity 43 (CAS CATO-C4X-144543)
- Tizanidine impurity 30 (CAS CATO-C4X-144530)
- Tizanidine impurity 027 (CAS 5391-42-4)
- Tizanidine impurity 21 (CAS CATO-C4X-144521)
Recommended Standards
- Methyl (6-chloro-7-hydroxy-4-methyl-2-oxo-2H-chromen-3-yl)acetate (CAS 500203-85-0)
- 3-Chloro-N-(3-ethoxypropyl)-5-(trifluoromethyl)-2-pyridinamine (CAS 1040309-94-1)
- Ethyl 3-[(2-chlorophenoxy)methyl]-1,2,4-oxadiazole-5-carboxylate (CAS 261962-50-9)
- 5-((5-Chloro-4-(methylamino)pyrimidin-2-yl)amino)-1-methyl-1H-pyrazole-3-carboxylic acid (CAS 1374829-42-1)
- Prucalopride Impurity 21 (CAS 2636673-48-6)
- Sofosbuvir Impurity 28 (CAS CATO-C4X-105228)
- Vildagliptin Impurity 94 HCl (CAS CATO-C4X-110094)
- 4'-Cyano-[1,1'-biphenyl]-4-yl 4-hexylbenzoate (CAS 59443-81-1)
- 2-(Aminomethyl)-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid (CAS 1558765-39-1)
- 4-Phenyl-5,6-dihydro-2H-pyran (CAS 3174-81-0)
- Omeprazole Impurity 29 (CAS 220757-74-4)
- 6-Pyrrolidin-1-ylnicotinonitrile (CAS 90839-82-0)
- 2-Oxo-5-(quinolin-2-yl)-1,2-dihydropyridine-3-carboxamide (CAS 115854-14-3)
- Peptide 439 (CAS CATO-CPTD788439)
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