Iopamidol Impurity 20 CAS CATO-C4X-145020
| CAS No. | CATO-C4X-145020 |
| Molecular Formula | C16H4Cl2I6N2O5 |
| Molecular Weight | 1136.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Iopamidol Impurity 20 (CAS CATO-C4X-145020) is a certified pharmaceutical impurity reference standard with the molecular formula C16H4Cl2I6N2O5 and a molecular weight of 1136.55 g/mol.
Structurally, Iopamidol Impurity 20 (C16H4Cl2I6N2O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 1136.55 g/mol, it falls into the high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H4Cl2I6N2O5 |
| Molecular Weight | 1136.55 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 2 |
Related Iopamidol Standards
- Iopamidol Impurity 28 (CAS 219851-75-9)
- Iopamidol Impurity 19 (CAS CATO-C4X-145019)
- Iopamidol Impurity 36 (CAS CATO-C4X-145036)
- Iopamidol EP Impurity E (CAS 60166-92-9)
- Iopamidol Impurity 51 (CAS CATO-C4X-145051)
- Iopamidol Impurity 26 (CAS CATO-C4X-145026)
- Iopamidol Impurity 50 (CAS CATO-C4X-145050)
- Iopamidol Impurity 56 (CAS CATO-C4X-145056)
Recommended Standards
- 1-(1-mercaptocyclohexaneacetic acid)-2-(O-ethyl-L-tyrosine)-4-L-valine-8-L-arginine-Vasopressin (CAS 77453-01-1)
- Caspofungin impurity 57 (CAS CATO-C4X-157557)
- C12-200 (CAS 1220890-25-4)
- Galanin (2-11) amide (CAS 367518-31-8)
- Emtricitabine impurity 56 (CAS 1962114-95-9)
- Roxatidine Impurity 39 (CAS CATO-C4X-121339)
- Zidovudine EP Impurity D (CAS 76-84-6)
- 2-tert-Butyl 8-ethyl 6-benzyl-2,6-diazaspiro[3.4]octane-2,8-dicarboxylate (CAS 1823261-82-0)
- 5-Chloro-N,N-dimethylpentan-1-amine hydrochloride (CAS 56824-25-0)
- 3-(Trifluoromethyl)phenyl 3-phenyl-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylate (CAS 478260-61-6)
- 4-(Naphthalen-1-yl)phthalazin-1(2H)-one (CAS 57835-94-6)
- 1-((4-Methoxyphenyl)sulfonyl)-1,2,3,4-tetrahydroquinolin-6-amine (CAS 1171141-87-9)
- Ethyl 2-furoate (CAS 1335-40-6)
- [y-Glu15]-Semaglutide Impurity 134 (CAS CATO-C4X-2226134)
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