Medroxyprogesterone Impurity 18 CAS CATO-C4X-145718
| CAS No. | CATO-C4X-145718 |
| Molecular Formula | C48H64O8 |
| Molecular Weight | 769.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Medroxyprogesterone Impurity 18 (CAS CATO-C4X-145718), a pharmacopoeial impurity reference standard (molecular formula C48H64O8, MW 769.02 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Medroxyprogesterone Impurity 18 (C48H64O8) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 17.0, corresponding to approximately 17 ring(s) or double-bond equivalent(s). With a molecular weight of 769.02 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C48H64O8 |
| Molecular Weight | 769.02 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Medroxyprogesterone Standards
- Medroxyprogesterone impurity 11 (CAS 2128317-86-0)
- Medroxyprogesterone Impurity 14 (CAS CATO-C4X-145714)
- Medroxyprogesterone Acetate Impurity 7 (CAS 28018-91-9)
- Medroxyprogesterone Acetate EP Impurity A (CAS 984-47-4)
- Medroxyprogesterone Impurity N1 (CAS 16319-93-0)
- Medroxyprogesterone impurity 8 (CAS 136803-81-1)
- Medroxyprogesterone Acetate Impurity 19 (CAS 71315-38-3)
- Medroxyprogesterone Acetate EP Impurity F (CAS 69688-15-9)
Recommended Standards
- Megestrol Acetate EP Impurity L (CAS CATO-C4X-141415)
- 6-((6-(Bis(4-methoxyphenyl)(phenyl)methoxy)hexyl)disulfanyl)hexyl (2-cyanoethyl) diisopropylphosphoramidite (CAS 148254-21-1)
- Megestrol Acetate EP Impurity L (CAS 3050754-59-8)
- [1,1′-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis[1,1-diphenylphosphine-κP]]iodo-copper (CAS 1218788-80-7)
- Ixazomib Impurity 79 (CAS 389799-97-7)
- Nafamostat Impurity 54 (CAS CATO-C4X-133254)
- N-Nitroso Fentanyl EP Impurity J (CAS 1184873-13-9)
- 5-Chloro-3-(1-methyl-1H-imidazol-2-yl)benzo[c]isoxazole (CAS 61689-21-2)
- 4-Amino-6-methylpicolinaldehyde (CAS 1289131-06-1)
- L-Alanine, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-n-[(9h-fluoren-9-ylmethoxy)carbonyl]-, methyl ester (CAS 336854-66-1)
- 4-Ethyl-5-methyl-3-phenyl-4,5-dihydroisoxazol-5-ol (CAS 449181-14-0)
- Tretinoin (CAS 302-79-4)
- 3-(2-Phenylethyl)pyridine (CAS 6312-09-0)
- Peptide Impurity 04 (CAS 2913424-91-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com