Megestrol Acetate EP Impurity L CAS 3050754-59-8
| CAS No. | 3050754-59-8 |
| Molecular Formula | C48H64O8 |
| Molecular Weight | 769.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Megestrol Acetate EP Impurity L (CAS 3050754-59-8), a pharmacopoeial impurity reference standard (molecular formula C48H64O8, MW 769.02 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system, Megestrol Acetate EP Impurity L is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 769.02 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C48H64O8 |
| Molecular Weight | 769.02 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
Related Megestrol Standards
- Megestrol Acetate EP Impurity L (CAS CATO-C4X-141415)
- Megestrol acetate EP Impurity G (CAS 1259198-59-8)
- Megestrol acetate EP Impurity H (CAS 907193-65-1)
- Megestrol Acetate EP Impurity I (CAS CATO-C4X-14149)
- Megestrol Acetate-d3 (CAS 162462-72-8)
- Megestrol Acetate EP Impurity J (CAS 14994-27-5)
- Megestrol Acetate EP Impurity C (CAS 74910-22-8)
- Megestrol Acetate EP Impurity D (CAS 32634-95-0)
Recommended Standards
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Why CATO?
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com