Phenylephrine Impurity 76 CAS CATO-C4X-146776
| CAS No. | CATO-C4X-146776 |
| Molecular Formula | C8H8Br2O2 |
| Molecular Weight | 295.96 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Phenylephrine Impurity 76 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Phenylephrine Impurity 76 (CAS CATO-C4X-146776), a pharmacopoeial impurity reference standard (molecular formula C8H8Br2O2, MW 295.96 g/mol) used for the identification and quantification of trace impurities in APIs.
Phenylephrine Impurity 76 (C8H8Br2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C8H8Br2O2 |
| Molecular Weight | 295.96 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
Related Phenylephrine Standards
- Phenylephrine Impurity 77 (CAS CATO-C4X-146777)
- Phenylephrine Impurity 75 (CAS CATO-C4X-146775)
- Phenylephrine Impurity 63 (CAS CATO-C4X-146763)
- Phenylephrine Impurity 64 (CAS CATO-C4X-146764)
- Phenylephrine Impurity 104 (CAS CATO-C4X-1467104)
- Phenylephrine Impurity 13 (CAS 830346-80-0)
- Phenylephrine Impurity 18 (Mixture of Diastereomers) (CAS 1217525-08-0)
- Phenylephrine Impurity 19 (CAS 915278-80-7)
Recommended Standards
- 3,5-Dibromo-4-ethoxypyridin-2-amine (CAS 89694-75-7)
- 2,6-dibromo-4-(2-hydroxyethyl)phenol (CAS 303009-05-4)
- 2-Bromo-1-(3-bromopropyl)-4-fluorobenzene (CAS 1057678-47-3)
- 2,5-Dibromo-1-(methoxymethoxy)benzene (CAS 2271442-85-2)
- 2,4-Dichlorobenzyl Alcohol EP Impurity F (CAS 874-42-0)
- Ramelteon Impurity 29 (CAS CATO-C4X-262229)
- Torasemide Impurity 9 (CAS 110363-51-4)
- 3-Acetyl-7-methoxy-2H-1-benzopyran-2-one (CAS 64267-19-2)
- 4-Chloro-7-methyl-1H-indole-6-carbonitrile (CAS 1167056-04-3)
- 3,5-Dinitro-1,1'-biphenyl (CAS 56813-80-0)
- 1-(2,6-Dicyclopropylpyrimidin-4-yl)-1,4-diazepane (CAS 1710195-40-6)
- (R)-2-Amino-2-(4-(ethylthio)phenyl)ethanol hydrochloride (CAS 1917356-29-6)
- 1,3-Benzenediol, polymer with 1,3-benzenediamine (CAS 51774-88-0)
- Semaglutide impurity 199 (CAS CATO-C4X-2226199)
Why CATO?
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