Indometacin Impurity 33 CAS CATO-C4X-147033
| CAS No. | CATO-C4X-147033 |
| Molecular Formula | C22H22ClNO5 |
| Molecular Weight | 415.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Indometacin Impurity 33 (CAS CATO-C4X-147033), a pharmacopoeial impurity reference standard (molecular formula C22H22ClNO5, MW 415.87 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C22H22ClNO5, Indometacin Impurity 33 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 415.87 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Indometacin Impurity 33 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H22ClNO5 |
| Molecular Weight | 415.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Indometacin Standards
- Indometacin Impurity 22 (CAS 78458-34-1)
- Indometacin Impurity 23 (CAS CATO-C4X-147023)
- Indometacin Impurity 31 (CAS CATO-C4X-147031)
- Indometacin Impurity 32 (CAS CATO-C4X-147032)
- Indometacin Impurity 34 (CAS CATO-C4X-147034)
- Indometacin Impurity 19 (CAS CATO-C4X-147019)
- Indometacin EP Impurity F (CAS 402849-27-8)
- Indometacin Impurity 21 (CAS 71848-87-8)
Recommended Standards
- (Z)-3-Chloro-N,N'-bis[(thiophen-2-yl)methyl]-5-(trifluoromethyl)pyridine-2-carboximidamide (CAS 338758-27-3)
- Benzyl ((3-chlorophenyl)(phenylsulfonyl)methyl)carbamate (CAS 1017782-73-8)
- ((4'-Chloro-[1,1'-biphenyl]-4-yl)sulfonyl)phenylalanine (CAS 1449133-06-5)
- Isavuconazole Impurity 32 (CAS 338990-31-1)
- Lovastatin Impurity 35 (CAS CATO-C4X-168435)
- (E)-Ceftizoxime Impurity 35 (CAS CATO-C4X-179335)
- Glycerol Impurity 6 (CAS 4217-84-9)
- Lithium (6-methoxypyridin-2-yl)trihydroxyborate (CAS 1393822-93-9)
- 2-Chloro-4-(3-ethylphenoxy)-5-fluoropyrimidine (CAS 1519398-68-5)
- 1-Methyl-4-phenyl-1h-imidazol-5-amine (CAS 1039984-25-2)
- 1-(4H-pyrrolo[2,3-b]pyrazin-7-yl)ethan-1-one (CAS 1522641-39-9)
- 5-Benzylidene-9-butyl-2,3,5,6,7,8-hexahydroacridin-4(1H)-one (CAS 105282-71-1)
- 2-(Benzyloxy)-5-fluoropyridin-3-ylboronic acid (CAS 1206776-48-8)
- Crustacean Cardioactive Peptide (CAS 107090-96-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com