Naltrexone impurity 51 CAS CATO-C4X-147551
| CAS No. | CATO-C4X-147551 |
| Molecular Formula | C22H21F6NO8S2 |
| Molecular Weight | 605.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Naltrexone impurity 51.
CATO supplies Naltrexone impurity 51 (CAS CATO-C4X-147551), a pharmacopoeial impurity reference standard (molecular formula C22H21F6NO8S2, MW 605.52 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C22H21F6NO8S2, Naltrexone impurity 51 contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 605.52 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H21F6NO8S2 |
| Molecular Weight | 605.52 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Naltrexone Standards
- Naltrexone impurity 55 (CAS CATO-C4X-147555)
- Naltrexone Impurity 69 (Mixture of Diastereomers) (CAS CATO-C4X-147569)
- Naltrexone impurity 39 (CAS CATO-C4X-147539)
- Naltrexone EP Impurity D (CAS 607732-61-6)
- Naltrexone-3-β-D-glucuronide (CAS 76630-71-2)
- Naltrexone Impurity 66 (CAS CATO-C4X-147566)
- Naltrexone impurity 40 (CAS CATO-C4X-147540)
- Naltrexone impurity 46 (CAS CATO-C4X-147546)
Recommended Standards
- Eldecalcitol Impurity 10 (CAS 200636-50-6)
- Tenofovir Impurity 125 (CAS 1796931-18-4)
- (E)-14-(4-((3-Ethynylphenyl)diazenyl)phenoxy)-13-oxo-3,6,9,12-tetraoxatetradecyl 2-bromo-2-methylpropanoate (CAS 1872365-88-2)
- Tenofovir disoproxil Impurity 13 (CAS 1244022-54-5)
- Benidipine Impurity 59 (CAS 61311-83-9)
- ErlotiniB impurity 35 (CAS CATO-C4X-106935)
- Posaconazole Impurity 253 (CAS CATO-C4X-1208254)
- (E)-N-(Pyridin-2-ylmethylene)aniline (CAS 40468-86-8)
- 3-(4-chloro-1h-pyraZol-1-yl)-2-methylpropanohydrazide (CAS 1005585-80-7)
- imidazo[1,2-a]pyrazin-6-amine (CAS 1159818-69-5)
- Prilocaine impurity 50 (CAS CATO-C4X-193450)
- Methyl vinylcarbamate (CAS 15204-93-0)
- (R,Z)-Ethyl 3-(2,2-dimethyl-1,3-dioxolan-4-yl)acrylate (CAS 104321-63-3)
- Autoinducing Peptide I trifluoroacetate salt (CAS 200010-29-3)
Why CATO?
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