Naltrexone Impurity 69 (Mixture of Diastereomers) CAS CATO-C4X-147569
| CAS No. | CATO-C4X-147569 |
| Molecular Formula | C38H42N2O8 |
| Molecular Weight | 654.75 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Naltrexone Impurity 69 (Mixture of Diastereomers) (C38H42N2O8) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Naltrexone Impurity 69 (Mixture of Diastereomers) (CAS CATO-C4X-147569) is a certified pharmaceutical impurity reference standard with the molecular formula C38H42N2O8 and a molecular weight of 654.75 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Naltrexone Impurity 69 (Mixture of Diastereomers) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C38H42N2O8 |
| Molecular Weight | 654.75 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Naltrexone Standards
- Naltrexone impurity 55 (CAS CATO-C4X-147555)
- Naltrexone impurity 39 (CAS CATO-C4X-147539)
- Naltrexone EP Impurity D (CAS 607732-61-6)
- Naltrexone Impurity 66 (CAS CATO-C4X-147566)
- Naltrexone impurity 51 (CAS CATO-C4X-147551)
- Naltrexone impurity 43 (CAS CATO-C4X-147543)
- Naltrexone impurity 52 (CAS CATO-C4X-147552)
- Naltrexone-3-β-D-glucuronide (CAS 76630-71-2)
Recommended Standards
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- (5-Phenyl-4,5-dihydro-1H-pyrazole-3,4-diyl)bis(phenylmethanone) (CAS 17416-51-2)
- 5,7-Dihydroxy-6,8-bis((4-methylpiperidin-1-yl)methyl)-3-(4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-4H-chromen-4-one (CAS 956976-99-1)
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