Lesinurad Impurity 9 CAS CATO-C4X-14789
| CAS No. | CATO-C4X-14789 |
| Molecular Formula | C18H15Br2N3O2S |
| Molecular Weight | 497.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 497.20 g/mol gives Lesinurad Impurity 9 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Lesinurad Impurity 9 (CAS CATO-C4X-14789) is a certified pharmaceutical impurity reference standard with the molecular formula C18H15Br2N3O2S and a molecular weight of 497.20 g/mol.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution, Lesinurad Impurity 9 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 497.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Lesinurad Impurity 9 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H15Br2N3O2S |
| Molecular Weight | 497.20 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Lesinurad Standards
- Lesinurad Impurity 18 (CAS CATO-C4X-147818)
- Lesinurad Impurity 5 (CAS CATO-C4X-14785)
- Lesinurad Impurity 10 (CAS 2250243-55-9)
- Lesinurad Impurity 31 (CAS 1533519-99-1)
- lesinurad M4 metabolite (CAS 2129551-55-7)
- Lesinurad Impurity 15 (CAS CATO-C4X-147815)
- Lesinurad Impurity 8 (CAS 1158970-52-5)
- Lesinurad impurity 16 (CAS CATO-C4X-147816)
Recommended Standards
- (E)-3-(3-((2,4-dichlorobenzyl)oxy)phenyl)-3-oxopropanal O-(2,6-dichlorobenzyl) oxime (CAS 478047-02-8)
- N-Phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]benzenamine (CAS 267221-89-6)
- (4-(2,3-Dichlorobenzoyl)-1H-pyrrol-2-yl)(4-(3,4-dichlorophenyl)piperazin-1-yl)methanone (CAS 477870-31-8)
- Ethyl 4-(2-(2-ethoxy-4-formyl-6-iodophenoxy)acetamido)benzoate (CAS 832677-97-1)
- Sorafenib Impurity 26 (CAS 1693-39-6)
- Ranitidine Impurity 23 (CAS CATO-C4X-137023)
- Cefathiamidine Impurity 8 (CAS CATO-C4X-13378)
- 3-Cyclopropoxy-N-methyl-5-(trifluoromethyl)isonicotinamide (CAS 1243346-83-9)
- 2-(3,4-Dimethylphenyl)-8-methylquinoline-4-carboxylic acid (CAS 438229-29-9)
- (S)-2-(aminomethyl)-3-methylbutan-1-ol hydrochloride (CAS 1266398-65-5)
- (R)-tert-Butyl 4-(fluoromethyl)-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide (CAS 2476729-49-2)
- (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-(oxetan-3-yl)acetic acid (CAS 2380894-05-1)
- 3-Bromo-2-chloro-5-iodobenzoic acid (CAS 860695-49-4)
- D-Leu26-Tirzepatide (CAS CATO-CPTD788908)
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