Lamotrigine Dimer Impurity 9 CAS 1797983-48-2
| CAS No. | 1797983-48-2 |
| Molecular Formula | C19H14Cl4N10 |
| Molecular Weight | 524.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Lamotrigine Dimer Impurity 9 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Lamotrigine Dimer Impurity 9 (CAS 1797983-48-2) is a certified pharmaceutical impurity reference standard with the molecular formula C19H14Cl4N10 and a molecular weight of 524.19 g/mol.
Structurally, Lamotrigine Dimer Impurity 9 (C19H14Cl4N10) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 524.19 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H14Cl4N10 |
| Molecular Weight | 524.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 10 |
Related Lamotrigine Standards
- Lamotrigine impurity 19 (CAS CATO-C4X-167219)
- Lamotrigine Dimer Impurity 8 (CAS CATO-C4X-16728)
- Lamotrigine Impurity 18 (CAS CATO-C4X-167218)
- Lamotrigine N2-Glucuronide (CAS 133310-19-7)
- Lamotrigine-2N-glucuronide (CAS 135288-68-5)
- Lamotrigine 5 N Glucuronide (CAS 136565-77-0)
- Lamotrigine EP Impurity F (CAS 252186-79-1)
- Lamotrigine Impurity 22 (CAS CATO-C4X-167222)
Recommended Standards
- 3'-O-Ac-dTTP (CAS 90290-82-7)
- 8-Br-PEt-cGMP (CAS 144510-04-3)
- (2E)-1-{3-[(2,4-dichlorophenyl)methoxy]phenyl}-3-[(4-iodophenyl)amino]prop-2-en-1-one (CAS 478040-36-7)
- 4-Bromo-N-(4-bromophenyl)-3-[[(phenylmethyl)amino]sulfonyl]benzamide (CAS 312756-74-4)
- Tegoprazan Impurity 149 (CAS CATO-C4X-2297149)
- Bilastine Impurity 12 HCl (CAS 2099128-83-1(Free base))
- Terbutaline EP impurity C (CAS 139508-58-0)
- (5-(4-(Trifluoromethyl)phenyl)pyridin-3-yl)methanol (CAS 885959-16-0)
- (1-Fluorocyclobutyl)methanamine (CAS 883311-84-0)
- 2-(4-Aminopiperidin-1-yl)-N-(2,4-dimethoxyphenyl)-acetamide dihydrochloride (CAS 1332530-10-5)
- 1-(adamantan-1-yl)-2-aminoethan-1-one hydrochloride (CAS 145256-72-0)
- 1-(Benzyloxy)-3-(3-fluorophenyl)benzene (CAS 1355247-13-0)
- tert-Butyl 3-formyl-4-methylpiperidine-1-carboxylate (CAS 1201187-01-0)
- Semaglutide Impurity 160 (x TFA Salt) (CAS CATO-C4X-2226160)
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