Loxoprofen Dihydroxy Impurity CAS 88378-22-7
| CAS No. | 88378-22-7 |
| Molecular Formula | C15H20O4 |
| Molecular Weight | 264.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Loxoprofen Dihydroxy Impurity (CAS 88378-22-7), a pharmacopoeial impurity reference standard (molecular formula C15H20O4, MW 264.32 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Loxoprofen Dihydroxy Impurity (C15H20O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures Loxoprofen Dihydroxy Impurity under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H20O4 |
| Molecular Weight | 264.32 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
Related Loxoprofen Standards
- Loxoprofen Impurity 160 (CAS CATO-C4X-1488160)
- Loxoprofen Impurity 56 (CAS 200554-09-2)
- Loxoprofen Impurity 149 (CAS CATO-C4X-1488149)
- Loxoprofen Impurity 131 (CAS CATO-C4X-1488131)
- Loxoprofen Impurity 146 (CAS CATO-C4X-1488146)
- Loxoprofen Impurity 15(Mixture of Diastereomers) (CAS 1091621-62-3)
- Loxoprofen Impurity 82 (CAS CATO-C4X-148882)
- Loxoprofen impurity 94 (CAS CATO-C4X-148894)
Recommended Standards
- (2R)-2-Phenylglycyl-glycine 1,1-Dimethylethyl Ester (CAS 439088-74-1)
- H-Phe-Val-OH (CAS 3918-90-9)
- Epoxymicheliolide (CAS 1343403-10-0)
- H-Val-Phe-OH (CAS 3918-92-1)
- Osimertinib Impurity 110 (CAS CATO-C4X-2045110)
- N-Nitroso Gentamicin impurity 30 (CAS CATO-C4X-148030)
- Lenalidomide Impurity 10 (CAS CATO-C4X-190310)
- 3-(Thiophen-2-yl)-5-(1-(thiophen-2-ylsulfonyl)piperidin-4-yl)-1,2,4-oxadiazole (CAS 946301-03-7)
- 3-chloroprop-2-ene-1-sulfonyl chloride (CAS 859056-31-8)
- (9H-Fluoren-9-yl)methyl 4-aminopiperidine-1-carboxylate hydrochloride (CAS 811841-89-1)
- Loxoprofen Impurity 154 (CAS 90319-74-7)
- 2-[(4-Aminophenyl)propan-2-yl]-4-thiazolecarboxylic Acid Hydrochloride (CAS 1538680-70-4)
- 2-(2-Chloropyridin-3-yl)acetaldehyde (CAS 1335054-88-0)
- Peptide Impurity 64 (CAS CATO-CPTD788964)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com