Cefprozil (Z)-isomer Impurity 48 CAS CATO-C4X-149248

Purity >90%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-149248
Molecular FormulaC18H19N3O5S
Molecular Weight389.43 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Cefprozil (Z)-isomer Impurity 48 CAS CATO-C4X-149248 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 389.43 g/mol gives Cefprozil (Z)-isomer Impurity 48 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

As a process- or degradation-related impurity, Cefprozil (Z)-isomer Impurity 48 (CAS CATO-C4X-149248, C18H19N3O5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Cefprozil (Z)-isomer Impurity 48 (C18H19N3O5S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H19N3O5S
Molecular Weight389.43 g/mol
Purity>90%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms3
Sulfur Atoms1

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