Itraconazole Impurity 22 CAS CATO-C4X-149722
| CAS No. | CATO-C4X-149722 |
| Molecular Formula | C43H39Cl4N11O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Itraconazole Impurity 22.
Itraconazole Impurity 22 (CAS CATO-C4X-149722) is a certified pharmaceutical impurity reference standard with the molecular formula C43H39Cl4N11O6 and a molecular weight of 947.66 g/mol.
Itraconazole Impurity 22 (C43H39Cl4N11O6) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Itraconazole Impurity 22 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C43H39Cl4N11O6 |
| Molecular Weight | 947.66 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 28.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 11 |
Related Itraconazole Standards
- Itraconazole Impurity 44 (CAS 103661-14-9)
- Itraconazole Impurity 41 (CAS 106461-41-0)
- Itraconazole Impurity 93 (CAS 110762-98-6)
- Itraconazole 2-Oxo Metabolite (CAS 112560-33-5)
- Itraconazole Impurity 38 (CAS 115897-54-6)
- Itraconazole N-Formyl-Ethlene Impurity (CAS 1199350-00-9)
- Itraconazole Impurity 73 (CAS 1199350-02-1)
- Itraconazole-d5(major) (CAS 1217510-38-7)
Recommended Standards
- Drotaverine Impurity 14 (CAS 5763-61-1)
- Desmopressin Impurity 35 (CAS CATO-C4X-221535)
- Parecoxib Impurity 43 (CAS 1373038-59-5)
- 1-Piperazinecarboxylic acid, 4-[5-bromo-3-(methoxycarbonyl)-2-pyridinyl]-, 1,1-dimethylethyl ester (CAS 1000018-22-3)
- 3,6-Dimethylmorpholine-2,5-dione (CAS 118363-62-5)
- 2-amino-N-(thiophen-2-ylmethyl)butanamide hydrochloride (CAS 1909313-29-6)
- Etrasimod Impurity 37 (CAS 2863533-56-4)
- N-benzylisochromane-1-carboxamide (CAS 889953-33-7)
- Bicyclo[2.2.1]heptan-2-yl formate (CAS 90199-27-2)
- Semaglutide Impurity 4 (CAS CATO-C4X-22264)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com