Itraconazole Impurity 76 CAS CATO-C4X-149776
| CAS No. | CATO-C4X-149776 |
| Molecular Formula | 2*C35H36Cl2N8O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Itraconazole Impurity 76 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Itraconazole Impurity 76 (CAS CATO-C4X-149776), a pharmacopoeial impurity reference standard (molecular formula C35H36Cl2N8O6, MW 735.62 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C35H36Cl2N8O6, Itraconazole Impurity 76 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 735.62 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | 2*C35H36Cl2N8O6 |
| Molecular Weight | 735.62 g/mol |
| Purity | ＞95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
Related Itraconazole Standards
- Itraconazole Impurity 44 (CAS 103661-14-9)
- Itraconazole Impurity 41 (CAS 106461-41-0)
- Itraconazole Impurity 93 (CAS 110762-98-6)
- Itraconazole 2-Oxo Metabolite (CAS 112560-33-5)
- Itraconazole Impurity 38 (CAS 115897-54-6)
- Itraconazole N-Formyl-Ethlene Impurity (CAS 1199350-00-9)
- Itraconazole Impurity 73 (CAS 1199350-02-1)
- Itraconazole-d5(major) (CAS 1217510-38-7)
Recommended Standards
- Sivelestat Impurity 12 (CAS CATO-C4X-212312)
- Bisoprolol Impurity 105 (CAS CATO-C4X-1247105)
- Lumateperone Impurity 73 (CAS CATO-C4X-220173)
- 3-(4-Chloro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)benzonitrile (CAS 1155075-44-7)
- (1,4-Diazepan-1-yl)(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanone (CAS 850411-05-1)
- H-Pro-Gly-OH (CAS 2578-57-6)
- Pyrimido[5,4-e][1,2,4]triazine-5,7(6H,8H)-dione (CAS 19359-69-4)
- 1-(3-Cyclobutoxyphenyl)ethan-1-one (CAS 863654-47-1)
- Octahydro-2,8,4,6-(epibutane[1,2,3,4]tetrayl)naphthalen-2(1H)-amine (CAS 77052-13-2)
- Tirzepatide Impurity 20 (CAS CATO-C4X-324020)
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