Itraconazole Methoxy IsopropyIrtiazolone Impurity CAS CATO-C4X-14979
| CAS No. | CATO-C4X-14979 |
| Molecular Formula | C22H27N5O2 |
| Molecular Weight | 393.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Itraconazole Methoxy IsopropyIrtiazolone Impurity (CAS CATO-C4X-14979) is a certified pharmaceutical impurity reference standard with the molecular formula C22H27N5O2 and a molecular weight of 393.48 g/mol.
The molecular framework of Itraconazole Methoxy IsopropyIrtiazolone Impurity (C22H27N5O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H27N5O2 |
| Molecular Weight | 393.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Itraconazole Standards
- Itraconazole Impurity 26 (CAS 89848-20-4)
- Itraconazole Impurity 41 (CAS 106461-41-0)
- Itraconazole Impurity 8 (CAS CATO-C4X-14978)
- Itraconazole Impurity 25 (CAS 89848-19-1)
- Itraconazole Methoxy ButyItriazolone Impurity (CAS CATO-C4X-149710)
- Itraconazole EP Impurity A (CAS 252964-68-4)
- Itraconazole Impurity 26（Relative stereochemistry） (CAS 67914-86-7)
- Itraconazole Impurity 38 (CAS 115897-54-6)
Recommended Standards
- LCZ-696 Impurity 4 (CAS 1038924-97-8)
- LCZ-696 Impurity 32 (CAS CATO-C4X-169632)
- Galanthamine Impurity 27 (CAS CATO-C4X-143527)
- Pemafibrate Impurity 9 (CAS CATO-C4X-29039)
- Folic Acid Impurity 52 (CAS CATO-C4X-139552)
- Relugolix Impurity 101 (CAS CATO-C4X-2429101)
- N-Nitroso Oxacillin Impurity 63 (CAS CATO-C4X-232163)
- N-[(3-Methyl-2-thienyl)methyl]cyclopentanamine Hydrochloride (CAS 869942-91-6)
- 4-(3-Chlorophenyl)-4-methylpiperidine-2,6-dione (CAS 1343463-05-7)
- tert-Butyl (S)-4-(4-(5-(aminomethyl)-2-oxooxazolidin-3-yl)-2-fluorophenyl)piperazine-1-carboxylate (CAS 268209-15-0)
- 1-(4-Nitrophenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 834894-65-4)
- (R)-1-(3-chlorophenyl)propan-1-amine hydrochloride (CAS 1168139-40-9)
- 2-(4-Chlorophenoxy) Propionic Acid (CAS 3307-39-9)
- D-[Phe]6-Semaglutide (CAS CATO-CPTD788633)
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