Doxofylline Impurity 36 CAS CATO-C4X-151336
| CAS No. | CATO-C4X-151336 |
| Molecular Formula | C5H12N4O |
| Molecular Weight | 144.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 144.17 g/mol gives Doxofylline Impurity 36 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Doxofylline Impurity 36 (CAS CATO-C4X-151336, C5H12N4O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Doxofylline Impurity 36 (C5H12N4O) is characterized by an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H12N4O |
| Molecular Weight | 144.17 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| Nitrogen Atoms | 4 |
Related Doxofylline Standards
- Doxofylline Impurity 24 (CAS 17743-04-3)
- Doxofylline Impurity 25 (CAS 6642-31-5)
- Doxofylline Impurity 34 (CAS CATO-C4X-151334)
- Doxofylline Impurity 29 (CAS 97-97-2)
- Doxofylline Impurity 22 (CAS 6632-68-4)
- Doxofylline Impurity 42 (CAS 56548-04-0)
- Doxofylline Impurity 32 (CAS 633296-51-2)
- Doxofylline Impurity 18 (CAS 42772-85-0)
Recommended Standards
- Duloxetine EP Impurity D (CAS 90-15-3)
- Clemastine Impurity 20 (CAS CATO-C4X-183720)
- Atorvastatin Impurity 52 (CAS 42558-54-3)
- Brivaracetam impurity 111 (CAS CATO-C4X-2007111)
- Sildenafil Impurity 42 (CAS 2146091-79-2)
- Piracetam impurity 37 (CAS CATO-C4X-123537)
- Perindopril EP Impurity O (CAS CATO-C4X-125272)
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- (2S,3S)-2-Amino-3-(1H-imidazol-4-yl)butanoic acid (CAS 1263377-71-4)
- N-methyl-2,3-dihydrobenzo[b]thiophene-2-carboxamide (CAS 1090962-89-2)
- (2,2-Dimethyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)boronic acid (CAS 1613450-45-5)
- 4-(4-Bromophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-1,3-thiazole (CAS 82100-81-0)
- Semaglutide impurity 22(OtBu-Ste-γGlu(OtBu)-AEEA-AEEA-OH) (CAS 1118767-16-0)
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