Perindopril EP Impurity O CAS CATO-C4X-125272
| CAS No. | CATO-C4X-125272 |
| Molecular Formula | C28H45N3O6 |
| Molecular Weight | 519.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Perindopril EP Impurity O (CAS CATO-C4X-125272) is a certified pharmaceutical impurity reference standard with the molecular formula C28H45N3O6 and a molecular weight of 519.67 g/mol.
Perindopril EP Impurity O (C28H45N3O6) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H45N3O6 |
| Molecular Weight | 519.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Perindopril Standards
- Perindopril EP Impurity H (CAS 353777-64-7)
- Perindopril Acyl-beta-D-Glucuronide (CAS 120398-66-5)
- Perindopril Benzyl Ester (CAS 122454-52-8)
- Perindopril EP Impurity G (CAS 353777-66-9)
- Perindopril Impurity 107 (CAS CATO-C4X-1252107)
- Perindopril Impurity 108 (CAS CATO-C4X-1252108)
- Perindopril Impurity 106 (CAS CATO-C4X-1252106)
- Perindopril Impurity 71 (CAS CATO-C4X-125271)
Recommended Standards
- ((1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(dimethyl(phenyl)silyl)-1-hydroxycyclopentane-1,2-diyl)dimethanol (CAS 701278-05-9)
- Boceprevir-d9 (CAS 1256751-11-7)
- Terpendole C (CAS 156967-65-6)
- (S)-N-(1-((4-methoxyphenyl)amino)-4-(methylthio)-1-oxobutan-2-yl)-1-tosylpiperidine-4-carboxamide (CAS 956439-77-3)
- Sulbactam Impurity 38 (CAS 69530-75-2)
- Miglitol Impurity 12 (CAS 305379-00-4)
- Lansoprazole Impurity 46 (CAS 86604-77-5)
- 4-(Piperazinyl)benzoic acid dihydrochloride, 97% (CAS 354813-11-9)
- 11,11-Difluoro-8-azadispiro[3.0.55.14]undecane hydrochloride (CAS 2098076-75-4)
- 5-Bromo-3-chloro-4-fluoropyridin-2-amine (CAS 2304366-53-6)
- Methyl 2-amino-2-methyl-5-(2-methyl-1h-imidazol-1-yl)pentanoate (CAS 1249812-96-1)
- (1aR,4aR,6S,7S,7aR,8R,11aS,E)-1,1,3,6-Tetramethyl-9-methylene-7-(nicotinoyloxy)-4-oxo-1a,4,4a,5,6,7,7a,8,9,10,11,11a-dodecahydro-1H-cyclopenta[a]cyclopropa[f][11]annulene-4a,8-diyl diacetate (CAS 218916-53-1)
- (3R,5R)-piperidine-3,5-diol (CAS 1043449-04-2)
- Tau Peptide (245-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 1428134-39-7)
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