Methylnaltrexone Bromide Impurity 5 CAS CATO-C4X-15215
| CAS No. | CATO-C4X-15215 |
| Molecular Formula | C21H25NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Methylnaltrexone Bromide Impurity 5 (CAS CATO-C4X-15215) is a certified pharmaceutical impurity reference standard with the molecular formula C21H25NO4Br and a molecular weight of 435.34 g/mol.
The molecular framework of Methylnaltrexone Bromide Impurity 5 (C21H25NO4Br) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Methylnaltrexone Bromide Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H25NO4 Br |
| Molecular Weight | 435.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Methylnaltrexone Standards
- Methylnaltrexone Bromide Impurity 4 (CAS 1005410-32-1)
- Methylnaltrexone Bromide Impurity 1 (CAS 1027638-96-5)
- Methylnaltrexone Bromide - API Standards (CAS 916055-92-0)
- Methylnaltrexone (CAS 916055-93-1)
- Methylnaltrexone Bromide Impurity 25 (CAS CATO-C4X-147525)
- Methylnaltrexone Bromide Impurity 10 (CAS CATO-C4X-152110)
- Methylnaltrexone Bromide Impurity 11 (CAS CATO-C4X-152111)
- Methylnaltrexone Bromide Impurity 12 (CAS CATO-C4X-152112)
Recommended Standards
- Visomitin Impurity 2 (CAS CATO-C4X-20822)
- Mirogabalin Impurity 82 (CAS 1246542-63-1)
- Riluzole Impurity 2 (CAS 752969-85-0)
- 6-Methyl-1,3-dioxaindane-5-carboxylic acid (CAS 5025-54-7)
- 4-(2-([1,1'-Biphenyl]-4-carbonyl)hydrazinyl)-4-oxobutanoic acid (CAS 304667-93-4)
- tert-Butyl 3-(2-aminophenyl)pyrrolidine-1-carboxylate (CAS 885270-26-8)
- Methyl 2-(4-bromo-5-(((tert-butyldimethylsilyl)oxy)methyl)-2-methylphenyl)acetate (CAS 1956340-19-4)
- tert-Butyl 2-butyl-4-oxopiperidine-1-carboxylate (CAS 919119-03-2)
- 4-((tert-Butoxycarbonyl)amino)-3,3-dimethylbutanoic acid (CAS 1310680-18-2)
- Heme iron polypeptide(Hematin) (CAS 14875-96-8)
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