Rebamipide Impurity 66 CAS CATO-C4X-152366

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-152366
Molecular FormulaC10H8BrNO2
Molecular Weight254.08 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Rebamipide Impurity 66 CAS CATO-C4X-152366 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 254.08 g/mol gives Rebamipide Impurity 66 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Rebamipide Impurity 66 (CAS CATO-C4X-152366), a pharmacopoeial impurity reference standard (molecular formula C10H8BrNO2, MW 254.08 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Rebamipide Impurity 66 (C10H8BrNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Rebamipide Impurity 66 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H8BrNO2
Molecular Weight254.08 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity≥95%
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentBr-containing
Nitrogen Atoms1

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