Spironolactone Impurity 12 CAS CATO-C4X-134512
| CAS No. | CATO-C4X-134512 |
| Molecular Formula | C24H38O3 |
| Molecular Weight | 374.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Spironolactone Impurity 12 (C24H38O3) contains a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Spironolactone Impurity 12 (CAS CATO-C4X-134512, C24H38O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Spironolactone Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H38O3 |
| Molecular Weight | 374.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Spironolactone Standards
- Spironolactone Impurity 15 (CAS CATO-C4X-134515)
- Spironolactone Impurity 18 (CAS CATO-C4X-134518)
- Spironolactone Impurity 11 (CAS 2537956-65-1)
- Spironolactone Impurity 19 (CAS CATO-C4X-134519)
- Spironolactone EP Impurity C (CAS 976-70-5)
- Spironolactone Impurity 16 (CAS CATO-C4X-134516)
- Spironolactone EP Impurity F (CAS 976-71-6)
- Spironolactone Impurity 17 (CAS CATO-C4X-134517)
Recommended Standards
- Ursodeoxycholic Acid Impurity 13 (CAS 5255-17-4)
- Ursodeoxycholic Acid impurity 106 (CAS CATO-C4X-1422106)
- cyclopropyl 2-(3,5-dimethylphenyl)ethyl ketone (CAS 898777-44-1)
- Ursodeoxycholic Acid Impurity 68 (CAS 62797-60-8)
- Obeticholic Acid Impurity 16 (CAS CATO-C4X-115316)
- Brimonidine Impurity 33 (CAS CATO-C4X-156633)
- Minoxidil Impurity 11 (CAS 56828-40-1)
- 1-(2-Chloro-4-(difluoromethoxy)phenyl)propan-1-one (CAS 1261776-30-0)
- 5-Bromo-2-cyanobenzenesulfonyl chloride (CAS 1257415-88-5)
- (S)-Tetrahydro-2H-pyran-3-ol (CAS 72886-97-6)
- 7-(Trifluoromethyl)-[1,2,4]triazolo-[4,3-a]pyridin-3(2H)-one (CAS 1613150-00-7)
- N-(Benzo[d][1,3]dioxol-5-ylmethyl)-N-methylpiperidin-4-amine hydrochloride (CAS 1417793-97-5)
- Methyl 2-(1-(aminomethyl)cyclobutyl)acetate (CAS 1515930-33-2)
- Neuropeptide AF (human) (CAS 192387-38-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com