Amorolfine Impurity 3 HCl CAS CATO-C4X-15423
| CAS No. | CATO-C4X-15423 |
| Molecular Formula | C21H35NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Amorolfine Impurity 3 HCl is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Amorolfine Impurity 3 HCl (CAS CATO-C4X-15423), a pharmacopoeial impurity reference standard (molecular formula C21H35NOHCl, MW 353.98 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Amorolfine Impurity 3 HCl (C21H35NOHCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 353.98 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H35NO HCl |
| Molecular Weight | 353.98 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Amorolfine Standards
- Amorolfine EP Impurity F (CAS 106614-66-8)
- Amorolfine Hydrochloride - Impurity G (CAS 1260498-34-7)
- Amorolfine EP Impurity G HCl (CAS 1260498-35-8)
- Amorolfine EP Impurity B (CAS 142347-84-0)
- Amorolfine Impurity 87 (CAS 1688675-10-6)
- Amorolfine Impurity 89 (CAS 1689944-83-9)
- Amorolfine Impurity 62 (CAS 1800302-57-1)
- trans-Amorolfine (CAS 2134097-34-8)
Recommended Standards
- Telmisartan Impurity 17 (CAS 1352492-08-0)
- Orniplabin impurity 3 (CAS CATO-C4X-35153)
- Desloratadine Impurity 48 (CAS 119770-61-5)
- 3-Bromo-2-(chloromethyl)-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 87779-01-9)
- 3-Cyclopropoxy-5-isopropoxyisonicotinonitrile (CAS 1243404-14-9)
- Arachidonyl Serotonin (CAS 187947-37-1)
- Secalciferol-d6 (CAS 1440957-55-0)
- 4-(2-(1,3-Dioxoisoindolin-2-yl)ethyl)thiomorpholine-3-carboxylic acid (CAS 1869520-38-6)
- Cyclopentanol (CAS 96-41-3)
- Peptide Impurity 40 (CAS CATO-CPTD788840)
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