Amorolfine Impurity 77 CAS CATO-C4X-154277
| CAS No. | CATO-C4X-154277 |
| Molecular Formula | C21H35NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Amorolfine Impurity 77 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Amorolfine Impurity 77 (CAS CATO-C4X-154277), a pharmacopoeial impurity reference standard (molecular formula C21H35NOHCl, MW 353.98 g/mol) used for the identification and quantification of trace impurities in APIs.
Amorolfine Impurity 77 (C21H35NOHCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Amorolfine Impurity 77 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H35NO HCl |
| Molecular Weight | 353.98 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Amorolfine Standards
- Amorolfine EP Impurity F (CAS 106614-66-8)
- Amorolfine Hydrochloride - Impurity G (CAS 1260498-34-7)
- Amorolfine EP Impurity G HCl (CAS 1260498-35-8)
- Amorolfine EP Impurity B (CAS 142347-84-0)
- Amorolfine Impurity 87 (CAS 1688675-10-6)
- Amorolfine Impurity 89 (CAS 1689944-83-9)
- Amorolfine Impurity 62 (CAS 1800302-57-1)
- trans-Amorolfine (CAS 2134097-34-8)
Recommended Standards
- Folic Acid EP Impurity E (CAS 1391068-26-0)
- Melatonin Impurity 30 (CAS 188396-95-4)
- Fluralaner Impurity 27 (CAS CATO-C4X-218027)
- 1H-Indole-1-carboxylic acid, 3-hydroxy-, 1,1-dimethylethyl ester (CAS 369595-02-8)
- (E)-3-(dimethylamino)-2-phenylmethoxyprop-2-enal (CAS 143462-35-5)
- Ethyl 2,2-difluorocyclopropanecarboxylate (CAS 151324-64-0)
- 1-(3-Bromo-5-fluorophenyl)-2-methylpropan-1-one (CAS 1147871-74-6)
- (R)-5-((9H-Fluoren-9-yl)methoxy)-4-((tert-butoxycarbonyl)amino)-5-oxopentanoic acid (CAS 214630-10-1)
- 2-(Difluoromethyl)-6-methoxy-4-methylpyridine-3-carboxamide (CAS 1806957-45-8)
- Neuropeptide Y (18-36) (CAS 114495-97-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com