Clofarabine Impurity 16 CAS CATO-C4X-159316
| CAS No. | CATO-C4X-159316 |
| Molecular Formula | C24H18ClN5 |
| Molecular Weight | 411.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Clofarabine Impurity 16 (CAS CATO-C4X-159316) is a certified pharmaceutical impurity reference standard with the molecular formula C24H18ClN5 and a molecular weight of 411.89 g/mol.
Based on its molecular formula C24H18ClN5, Clofarabine Impurity 16 contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 411.89 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Clofarabine Impurity 16 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H18ClN5 |
| Molecular Weight | 411.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Clofarabine Standards
- Clofarabine Impurity 10 (CAS CATO-C4X-159310)
- Clofarabine Impurity 9 (CAS CATO-C4X-15939)
- Clofarabine Impurity 6 (CAS 97614-43-2)
- Clofarabine Impurity N2 (CAS 704916-12-1)
- Clofarabine Impurity 8 (CAS 111615-20-4)
- Clofarabine Impurity 5 (CAS 14215-97-5)
- Clofarabine Impurity 4 (CAS 70832-64-3)
- Clofarabine (CAS 123318-82-1)
Recommended Standards
- Mandipropamid (CAS 374726-62-2)
- 1-Bromo-5-iodo-4-nitro-2-(trifluoromethoxy)benzene (CAS 1187386-19-1)
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- (4-Chlorophenyl)methyl N-[4,6-dimethyl-3-(1H-pyrrol-1-yl)thieno[2,3-b]pyridin-2-yl]carbamate (CAS 866039-17-0)
- Temozolomide Impurity 22 (CAS 1114912-01-4)
- Relebactam Impurity 40 (CAS CATO-C4X-214440)
- Sivelestat sodium Impurity 5 (CAS 127373-95-9)
- 2-Bromo-3-(difluoromethyl)benzonitrile (CAS 1261495-80-0)
- 5-(2-(Dimethylamino)pyrimidin-4-yl)furan-2-carboxylic acid (CAS 1399655-32-3)
- Dopamine Impurity 44 (CAS CATO-C4X-190844)
- 3-Bromo-N-(cyclopropylmethyl)-4-methoxyaniline (CAS 536694-68-5)
- 2-((2-((tert-Butoxycarbonyl)amino)cyclohexyl)(ethyl)amino)acetic acid (CAS 1353980-64-9)
- 1-Chloro-3-(1-trifluoromethyl-cyclopropyl)-benzene (CAS 1936191-72-8)
- [D-Phe22]Semaglutide (CAS CATO-C4X-2226222)
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